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There is a Legacy version here.

Amphisbaena

An amphisbaena is an exceedingly aggressive, venomous viper of remarkable size that bears two heads—one on each end of its body. It moves in a manner similar to the more common sidewinder snake, throwing its body forward in a loop and anchoring itself by keeping one head or the other on the ground at all times. An amphisbaena can grow up to 14 feet in length and weigh as much as 250 pounds.

Amphisbaenas' typical prey include rabbits, foxes, various birds, small deer, and even humanoids if presented the opportunity. Fiercely territorial by nature, they attack just about anything that draws near their lairs regardless of the intruder's size. Many a child has been warned about going too far into the woods alone, lest they wander close to an amphisbaena's den and become the creature's next meal.

The venom of an amphisbaena is incredibly potent, able to take down a stout dwarf within minutes if left untreated. It also has uses in a variety of healing remedies, however, which makes it a valuable commodity if collected. For example, a pregnant person might be advised to drink the venom in small, dilute doses to help safeguard the pregnancy. Mixing small amounts of the venom with various herbs and oil creates a poultice that dulls aches and pains. As a result, the image of an amphisbaena appears in many contexts associated with healing or alchemical subjects, such as labels for tinctures, annotations in herbalists' records, and illustrations in textbooks of medicine.

The first amphisbaena is said to have formed from the blood that fell as a medusa's head was severed. This story's origin most likely stems from the fact that amphisbaenas are oddly immune to petrification, which in turn sometimes leads them to be kept as pets by medusas. A medusa might regard such a viper as their most treasured companion or perhaps even as their own child. Despite these fabled supernatural origins and the occasional special treatment they receive, though, amphisbaenas are entirely mundane animals with only rudimentary intelligence and no innate magical abilities whatsoever.

Recall Knowledge - Animal (Nature): DC 19
Unspecific Lore: DC 17
Specific Lore: DC 14

Elite | Normal | Weak
Proficiency without Level

AmphisbaenaCreature 4

Medium Animal 
Source Monster Core 2 pg. 25
Perception +7; tremorsense 60 feet
Skills Acrobatics +6, Athletics +9, Stealth +8
Str +5, Dex +4, Con +2, Int -4, Wis +0, Cha -4
AC 16 all-around vision; Fort +7, Ref +10, Will +4
HP 70; Immunities petrified
Speed 25 feet, climb 25 feet, swim 25 feet
Melee [one-action] fangs +9 [+4/-1], Damage 2d6+5 piercing plus amphisbaena venomRanged [one-action] spit +8 [+3/-2] (range increment 15 feet), Damage 1d6 poison plus amphisbaena venom and blinding spittleAmphisbaena Venom (poison) Saving Throw DC 14 Fortitude; Maximum Duration 6 rounds; Stage 1 1d6 poison damage and enfeebled 1 (1 round); Stage 2 2d6 poison damage and enfeebled 2 and slowed 1 (1 round); Stage 3 3d6 poison damage and paralyzed for 1 round (1 round)Blinding Spittle A creature critically hit by an amphisbaena's spit Strike is blinded for 1 round.Twin Bites [one-action] An amphisbaena makes a fangs Strike with each of its heads, each against a different target. Both Strikes count toward its multiple attack penalty, but the penalty doesn't increase until after it has made both attacks.

Sidebar - Related Creatures Amphisbaena Variants

While the two-headed snake is by far the most common amphisbaena, the term sometimes describes other creatures with heads on both ends of their bodies. Occasionally, stories circulate of a monstrous amphisbaena with the body of a lizard, clawed feet, or even feathered wings. These stories are typically chalked up to an overactive imagination or an abundance of drink, but they persist regardless.